ALTG 13/008 PEARL: A randomised phase 2 trial of early referral to palliative care for patients with advanced thoracic malignancies – L Mileshkin, J Yoong

PEARL is a non-blinded, randomised Phase III study of early referral to palliative care for patients with advanced thoracic cancer. This multicentre, international trial is a collaboration between the ALTG, Palliative Care Clinical Studies Collaborative and NHMRC Clinical Trials Centre. The study received ethics approval in October 2016 with a plan to recruit 200 patients across up to 25 sites in Australia and New Zealand over a 2 year period, starting in Q2 2017.

The study will evaluate whether early referral to palliative care improves Health-Related Quality of Life, overall survival and use of health care resources in patients with recently diagnosed, advanced thoracic malignancies.

State/TerritorySitePIActivation DateRecruitment
NSWCampbelltown HospitalAnnette Tognela
Concord HospitalPrunella Blinman
Liverpool HospitalRebecca Strutt
Port Macquarie - MNCCIBaerin Houghton
Riverina Cancer Care CentreRenuka Chittajallu
Royal North Shore HospitalNick Pavlakis
The Tweed HospitalEhtesham Abdi
Westmead HospitalRina Hui
QLDRadiation Oncology Centre - Gold CoastDominic Lunn
The Prince Charles HospitalHenry Marshall
Townsville HospitalSuresh Varma
Toowoomba HospitalPatricia Lourdes Lee-Apostol
VICBarwon HealthPeter Martin
Eastern HealthPhillip Parente
Monash HealthPeter Poon
Peter MacCallum Cancer Centre including Royal Melbourne HospitalLinda Mileshkin - Study Chair
St Vincent's HospitalJennifer Phillip
SASouthern Adelaide Palliative ServicesPeter Allcroft
WASir Charles Gairdner HospitalRajesh Thomas

Study Contacts

Study Chair: Linda Mileshkin

CTC Trial Coordinator: David Cannan

Upcoming Events

28 August 2017 12.00am TACT Board Teleconference (closed)
8 September 2017 12.00am ESMO 2017 Congress, Madrid Spain
6 October 2017 12.00am ***UPDATED*** 3rd ALTG Preceptorship in Lung Cancer, Melbourne VIC
15 October 2017 12.00am TACT General Assembly (closed), Yokohama Japan
15 October 2017 12.00am 18th WCLC, Yokohama Japan
24 November 2017 12.00am ***UPDATED*** 2017 ALTG Lung Cancer Symposium, Sydney NSW
24 November 2017 12.00am ***UPDATED*** ALTG Members’ Meeting, Sydney NSW